Keystones

Dwarf Spheroidal Galaxies : Keystones of Galaxy Evolution

Dwarf spheroidal galaxies are the most insignificant extragalactic stellar systems in terms of their visibility, but potentially very significant in terms of their role in the formation and evolution of much more luminous galaxies. We discuss the present observational data and their implications for theories of the formation and evolution of both dwarf and giant galaxies. The putative dark matt...

Legally Fair Contract Signing Without Keystones

In two-party computation, achieving both fairness and guaranteed output delivery is well known to be impossible. Despite this limitation, many approaches provide solutions of practical interest by weakening somewhat the fairness requirement. Such approaches fall roughly in three categories: “gradual release” schemes assume that the aggrieved party can eventually reconstruct the missing informat...

Challenges in the Quest for Keystones

Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host response.

Recent studies have uncovered novel mechanisms underlying the breakdown of periodontal host-microbe homeostasis, which can precipitate dysbiosis and periodontitis in susceptible hosts. Dysbiotic microbial communities of keystone pathogens and pathobionts are thought to exhibit synergistic virulence whereby not only can they endure the host response but can also thrive by exploiting tissue-destr...

Spotting Epidemic Keystones by R0 Sensitivity Analysis: High-Risk Stations in the Tokyo Metropolitan Area

How can we identify the epidemiologically high-risk communities in a metapopulation network? The network centrality measure, which quantifies the relative importance of each location, is commonly utilized for this purpose. As the disease invasion condition is given from the basic reproductive ratio R0, we have introduced a novel centrality measure based on the sensitivity analysis of this R0 an...